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Letter "F" » Fred Kaplan Quotes
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«The Wizards of Armageddon.»
Author: Fred Kaplan
«This is catastrophic beyond belief,»
Author: Fred Kaplan
«What happens in FOP is children continue to make new pieces of the skeleton after birth, ... The signal is not just 'make more bone.'»
Author: Fred Kaplan
«You can't keep a child in a glass box,»
Author: Fred Kaplan
«That can send the condition into a wild state of flare-up.»
Author: Fred Kaplan
«[Life expectancy for people with FOP is] tremendously variable, ... The average life span is mid-40s, but it ranges from the teens to the 80s.»
Author: Fred Kaplan
«These people are literally imprisoned in a second skeleton, ... It transforms muscles, tendons, ligaments -- connective tissues become sheathed in bone. It spans joints, locking them into place and rendering movement completely impossible.»
Author: Fred Kaplan
«[Several proteins have been identified as vital for bone growth, including one called BMP4.] We know BMP4 is one of the terrorist agents that triggers new bone formation, ... We're working on therapies to limit the production of BMP4 in people who have FOP.»
Author: Fred Kaplan
«Even if the answer to FOP is only for FOP, it wouldn't in any way dissuade me from working on it, ... I would hope we can make a difference for these kids (and find) medications, treatment or therapy that would enable them to prevent a joint from turning into bone or restore movement to some joint already frozen.»
Author: Fred Kaplan
«Generally, though, these people are quite healthy, ... Perhaps there is an auto-inflammatory component because they tend to be tremendously resistant to infections. But if they happen to get a cold or respiratory infection, it's more likely to become a complicated issue.»
Author: Fred Kaplan
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